Viewing data from:

ESTRADIOL

ANDA

ESTRADIOL | A217610 | NOVITIUM PHARMA LLC

5 strengths0 unique patents0 unique exclusivities

Reference Listed Drug: DIVIGEL(TE code: AB)

Drug Pricing (NADAC)

National Average Drug Acquisition Cost — Week of 2026-07-15 | 10 NDCs

Highest NADAC/Unit

$1.51

per ea

Lowest NADAC/Unit

$1.14

per ea

Brand NDCs

Generic NDCs

NDC Description	NADAC/Unit	Unit	Type	Generic NADAC	Effective
70954053320ESTRADIOL 0.1% (1 MG) GEL PKT	$1.51	GM	Generic	—	2026-06-17
72603024430ESTRADIOL 0.1% (1 MG) GEL PKT	$1.51	GM	Generic	—	2026-06-17
70954053120ESTRADIOL 0.1% (0.25 MG) GEL PK	$1.38	EA	Generic	—	2026-06-17
72603024130ESTRADIOL 0.1% (0.25 MG) GEL PK	$1.38	EA	Generic	—	2026-06-17
72603024330ESTRADIOL 0.1% (0.75 MG) GEL PK	$1.34	EA	Generic	—	2026-06-17
70954053220ESTRADIOL 0.1% (0.75 MG) GEL PK	$1.34	EA	Generic	—	2026-06-17

Showing 6 of 10 NDCs.

Source: NADAC (data.medicaid.gov). Prices reflect national average acquisition costs for retail community pharmacies.

VA Federal Supply Schedule

Government-negotiated contract prices | 5 NDCs (5 FSS)

Lowest Price

$49.76

Highest Price

$49.76

FSS NDCs

Big4 NDCs

Description	Price	Type	Vendor	Contract End
70954-0530-20ESTRADIOL 0.1% 0.5MG/PKT GEL,TOP	$49.76	FSS	Marlex Pharmaceuticals, Inc.	01/31/2030
70954-0531-20ESTRADIOL 0.1% 0.25MG/PKT GEL,TOP	$49.76	FSS	Marlex Pharmaceuticals, Inc.	01/31/2030
70954-0532-20ESTRADIOL 0.1% 0.75MG/PKT GEL,TOP	$49.76	FSS	Marlex Pharmaceuticals, Inc.	01/31/2030
70954-0533-20ESTRADIOL 0.1% 1MG/PKT GEL,TOP	$49.76	FSS	Marlex Pharmaceuticals, Inc.	01/31/2030
70954-0534-20ESTRADIOL 0.1% 1.25MG/PKT GEL,TOP	$49.76	FSS	Marlex Pharmaceuticals, Inc.	01/31/2030

Source: VA Federal Supply Schedule (va.gov). Prices are government-negotiated contract prices.

API Supply Chain12 active DMFs19 inactive

10 active API suppliers hold Drug Master Files for this ingredient.

ASPEN OSS BVESTRADIOL

DMF 38291980

GEDEON RICHTER PLCESTRADIOL USP

DMF 40661981

BAYER AGESTRADIOL

DMF 46841982

KINDEVA DRUG DELIVERY LPESTRADIOL TRANSDERMAL DRUG DELIVERY SYSTEM

DMF 98411992

VALDEPHARMESTRADIOL HEMIHYDRATE

DMF 229722009

VALDEPHARMESTRADIOL BENZOATE

DMF 238362010

ZHEJIANG XIANJU PHARMACEUTICAL CO LTDESTRADIOL HEMIHYDRATE USP, NON-STERILE, BULK DRUG SUBSTANCE

DMF 239422010

LUPIN LTDESTRADIOL HEMIHYDRATE USP

DMF 258162012

SYMBIOTEC PHARMALAB PRIVATE LTDESTRADIOL HEMIHYDRATE USP

DMF 341472019

ASPEN OSS BVESTRADIOL 3-ACETATE

DMF 347382020

HUBEI GEDIAN HUMANWELL PHARMACEUTICAL CO LTDESTRADIOL HEMIHYDRATE

DMF 435612026

YANGZHOU AURISCO PHARMACEUTICAL CO LTDESTRADIOL HEMIHYDRATE

DMF 439512026

SCHERING AGInactiveESTRADIOL ENANTHATE

DMF 10931967

ORTHO PHARMACEUTICAL CORPInactiveESTRADIOL 17-A-IN PROPYLENE GLYCOL : PARENTERAL

DMF 16551971

ROUSSEL CORPInactiveESTRADIOL BENZOATE

DMF 22911974

ORGANON INCInactiveESTRADIOL

DMF 26771976

MITSUBISHI CHEMICAL INDUSTRIES LTDInactiveESTRADIOL

DMF 31751978

DIOSYNTH BVInactiveESTRADIOL BENZOATE

DMF 35801979

MEDIMPEX NORTHAMERICA INCInactiveESTRADIOL DIPROPIONATE

DMF 40731981

DIOSYNTH BVInactiveESTRADIOL VALERATE MICRO

DMF 42671981

ROUSSELL UCLAFInactiveESTRADIOL USP

DMF 56861985

DR REDDYS LABORATORIES LTDInactiveESTRADIOL

DMF 69461987

ROUSSELL UCLAFInactiveESTRADIOL

DMF 88191990

PHARMACIA AND UPJOHN SUB PFIZER INCInactiveESTRADIOL

DMF 105361993

CYGNUS INCInactiveESTRADIOL TRANSDERMAL DELIVERY SYSTEM (E2 III TDS)

DMF 106511993

NV ORGANONInactiveESTRADIOL BENZOATE

DMF 150852000

DIOSYNTH BVInactiveESTRADIOL GLUCOSIDE

DMF 157592001

MILLICENT HOLDINGS LTDInactiveESTRADIOL 3 ACETATE

DMF 161202002

CATALENT PHARMA SOLUTIONS LLCInactiveESTRADIOL VAGINAL SOFT GELATIN CAPSULES

DMF 228432009

BEIJING KEYIFENG BIOTECH DEVELOPMENT CO LTDInactiveESTRADIOL USP, NON-STERILE, BULK DRUG

DMF 240852010

ZHEJIANG XIANJU JUNYE PHARMACEUTICAL CO LTDInactiveESTRADIOL

DMF 241922010

Source: FDA Drug Master Files (fda.gov). Type II API DMFs matched by ingredient.